Near-Infrared Spectroscopy (NIRS) and diffuse correlation spectroscopy (DCS) are two established techniques which allow monitoring brain health non-invasively.

With the foundation of our seminal NIRS-DCS work on neonates, we are developing novel devices and approaches to better quantify cerebral blood oxygenation, cerebral blood flow and oxygen metabolism in the clinical setting both in children and adults. In particular, in the last few years we have made substantial progress on DCS technology to improve depth sensitivity, speed and accuracy of the recovered blood flow index.

In this presentation I will review the latest technology developments which are going to enable routine use of NIRS and DCS as clinical and wearable technologies. Finally, I will focus on the adoption of these techniques in clinical applications and present results of our latest studies in children and adults.