Régine Denesle
Sessions in which Régine Denesle attends
Not scheduled
Although social distancing directives are important public health measures to reduce the spread of SARS-cov-2, they can contribute to negative emotional outcomes such as loneliness due to the isolation. Furthermore, individuals have been reporting poorer sleep quality since the beginning of the COVID-19 pandemic. The aim of this study is to...
The effects of physical inactivity among older adults have been established as a "public health crisis" because of their heightened risk of cardiovascular, autoimmune, neurocognitive, and mental health problems (Wu, 2020). While physical distancing is essential in the fight against COVID-19, long-term self-isolation protocols established to protect the elderly population have created new health risks, as older adults are now left more socially isolated and inactive than before. Making an inve...
Evidence consistently demonstrates that aging is associated with declines to cerebrovascular health. Sex distinctions have been identified as well, where studies have shown that cerebral blood flow (CBF) declines linearly across the lifespan in both sexes, yet females have greater CBF compared to males [1]. Cerebrovascular reactivity (CVR) has also been identified as a marker of cerebrovascular health and is shown to decline with age [1,2], but the potential sex differences are currently uncl...
According to the oxidative stress theory, reactive species are key drivers of inflammation and cardiovascular disease (1). The electron transport chain of the mitochondria accounts for ≈90 of the intracellular radioactive oxygen species (2). Interestingly, while low-carbohydrate high-protein diets promote weight loss, animal experiments show that they could also lead to mitochondrial dysfunction and therefore, oxidative stress and inflammation (3). In parallel, research in the last decade has...
Monday 10 May, 2021
In this talk, we will present our recent developments in the context of Personalized functional Near Infra-Red Spectroscopy (fNIRS) investigations, which consist in optimizing placement of fNIRS sources and detectors on the head of the participant in order to maximize fNIRS sensitivity to some targeted brain regions, while allowing accurate local 3D reconstructions of fluctuations of oxy-hemoglobin and deoxy-hemoglobin along the cortical surface. Personalized fNIRS investigations could be ...
The following posters will be presented:2:45pm-2:50pmThe Child Focused Injury Risk Screening Tool (ChildFIRST) - Normative Values, Correlations, and Sex Differences for a group of Children aged 8-12Presented by: Matthew B. Miller2:50pm-2:55pmArt-based Rehabilitation Therapy (ART) for Sensorimotor Recovery Post-stroke: A Pilot StudyPresented by: April Christiansen2:55pm-3:00pmWhite matter micros...
Tuesday 11 May, 2021
Sleep is important for memory consolidation and cognitives performances during the day. There is increasing evidence that brain oscillations during sleep play a central role in such processes. This presentation will review recent work from our lab on the interplay between brain rhythms during sleep, memory consolidation and age-related cognitive decline. We will also discuss recent data showing the impact of sleep disturbances on cognitive functions, as well as the effects o...
The following posters will be presented:10:45am-10:50amThe Belief in Health Benefits of Digital Play Modulates Physiological Responses to Games Played for Cognitive BenefitsPresented by: Sasha Elbaz10:50am-10:55amEffects of Injury Prevention Strategies on the Biomechanics and Neuromuscular Performance of Fundamental Movement Skills in Children and Adolescents.Presented by: John A. Jimenez-Garcia10:55am-11:00am
Circadian clock genes are widely expressed in mammalian brain. Despite considerable knowledge about the role of these genes in the generation of circadian rhythms in the suprachiasmatic nucleus, the master circadian clock, insight into brain-region specific function of these genes limited. Studies in our laboratory investigate the role of core clock gene, Bmal1 and Per2 in the control of behaviors governed by the striatum, a forebrain structure critical in in motor control, reward processi...
The following posters will be presented:2:45pm-2:50pmLoneliness and sleep quality during the COVID-19 pandemic: A longitudinal studyPresented by: Jude Nachabe2:50pm-2:55pmAcute Effects of Urolithin A on Mitochondrial Respiration in Vascular Smooth Muscle Cells of ApoE-/- MicePresented by: Jesse Corbin2:55pm-3:00pmAssociation between physical activity and psychological distress during COVID-19: ...
Wednesday 12 May, 2021
Regional brain function is determined by its local structure and connectivity. I will present work from our lab that strives to quantify connectivity for applications in healthy development and understanding the impact of disease - focusing on understanding normative cerebellar connectivity and quantifying the impact of stroke. I will also touch on some recent work linking interhemispheric functional connectivity to bimanual motor control in older adults.