Anthoula Mantis
Sessions in which Anthoula Mantis attends
Not scheduled
Background: During atherosclerotic plaque development, vascular smooth muscle cells (VSMC) undergo dedifferentiation, resulting in a synthetic, less contractile progenitor state. This transition is marked by changes in mitochondrial respiration and increased reactive oxygen species (ROS) production. These changes in bioenergetics play a critical role in atherogenesis via facilitation of VSMC migration towards the intima. Objective: The objective of this study was to evaluate t...
Efficient neural transmission is crucial for optimal brain function, yet the plastic potential of white matter (WM) has long been overlooked. Growing evidence now shows that modifications to axons and myelin occur not only as a result of long-term learning, but also after short training periods [1]. Motor sequence learning (MSL) has been shown to occur in overlapping learning stages where different neural circuits are involved at each stage [2]. However, most studies investigating short-term ...
Background: Cellular senescence, cell growth cycle arrest, is a marker of cellular aging. Obesity is considered a disease of accelerated aging as it shares several co-morbidities with aging, such as type 2 diabetes mellitus (T2DM). Objective: To determine regional differences in markers of cellular senescence and how these compare in obese individuals with and without T2DM. Methods: Pre-menopausal females undergoing bariatric surgery were categorized as obese-metabolically healthy...
Evidence consistently demonstrates that aging is associated with declines to cerebrovascular health. Sex distinctions have been identified as well, where studies have shown that cerebral blood flow (CBF) declines linearly across the lifespan in both sexes, yet females have greater CBF compared to males [1]. Cerebrovascular reactivity (CVR) has also been identified as a marker of cerebrovascular health and is shown to decline with age [1,2], but the potential sex differences are currently uncl...
Although social distancing directives are important public health measures to reduce the spread of SARS-cov-2, they can contribute to negative emotional outcomes such as loneliness due to the isolation. Furthermore, individuals have been reporting poorer sleep quality since the beginning of the COVID-19 pandemic. The aim of this study is to...
Context: While soccer is considered a lateral dominant sport, few studies have examined if limb dominancy leads to asymmetries in body composition and their possible associations with injury (1). Objective: The purpose of this study was to 1) investigate body composition morphological asymmetries in male and female university-level soccer players, and 2) examine whether the degree of body composition asymmetry is associated with lower leg injuries (LLI) and lower back pain (LBP...
Background: Recovery kinetics following cardiopulmonary exercise testing (CPET) have yet not been described in people with OSA and comorbid insomnia (COMISA). Our objectives were to i) describe heart rate recovery (HRR), oxygen recovery slopes (VO2/t) and time to half recovery of VO2max (T½) following CPET in COMISA; and ii) investigate their response to either one of the following: 16 weeks of exercise training (Ex) or 8 week-relaxation control intervention followed by 8 weeks of exercise an...
Childhood obesity and physical inactivity are growing problems across Canada, so the concept of physical literacy is used to promote physical activity (PA) participation in children. When children increase their PA participation, their exposure to musculoskeletal injury is also increased, but the concepts of physical literacy do not address...
Postural stability is a complex skill dependent upon the coordination of motor, sensory and cognitive systems (Woollacott & Shumway-Cook, 2002). The purpose of this project was therefore to explore how older adults' balance performance is impacted by increased cognitive load, hearing loss, and simulated vision loss. Twenty-seven older adults between the ages of 56 and 90 years (M = 74.74, SD = 9.51) were tested. Participants underwent standard sensory acuity, and cognitive functioning tes...
Background: Different exercise intensity has a various effect on the immune system. Lactate is one of the factors that releases in exercise, on one hand, higher lactate concentration not also apoptosis of peripheral blood mononuclear cells (PBMCs) decrease but also the survival of the PBMCs increase (Elsaser et al., 2017), on the other hand...
Background: To create games that target older adults' interests in engaging in cognitively-boosting activities is a rising trend [1,2]. But, the novelty of the digital me-dium of play, and the implicit expectation of cognitive performance can create stressful experiences for them [3]. We have previously proposed an empirical framework, Affective Game Planning for Health Applications (AGPHA) based on Lazarus's Transactional Theory of Stress Appraisal and Coping [4], to study interactions betwe...
According to the oxidative stress theory, reactive species are key drivers of inflammation and cardiovascular disease (1). The electron transport chain of the mitochondria accounts for ≈90 of the intracellular radioactive oxygen species (2). Interestingly, while low-carbohydrate high-protein diets promote weight loss, animal experiments show that they could also lead to mitochondrial dysfunction and therefore, oxidative stress and inflammation (3). In parallel, research in the last decade has...
The effects of physical inactivity among older adults have been established as a "public health crisis" because of their heightened risk of cardiovascular, autoimmune, neurocognitive, and mental health problems (Wu, 2020). While physical distancing is essential in the fight against COVID-19, long-term self-isolation protocols established to protect the elderly population have created new health risks, as older adults are now left more socially isolated and inactive than before. Making an inve...
Introduction: Right to left asymmetries in body composition has been examined across many sports, suggesting possible implications for lower back pain (LBP) and decreased level performance. However, we are not aware of any study that has examined the presence and implications of morphological asymmetries in ice hockey players. The purpose of this study was to 1) investigate body composition asymmetries in female and male university level ice hockey players and 2) examine whether the degree of...
Monday 10 May, 2021
The following posters will be presented:11:00am-11:05amThe Potential of Probiotics in Preventing Diet-Induced Mitochondrial DysfunctionPresented by: Antoine St-Amant11:05am-11:10amBody composition asymmetries in university ice hockey players and their implications for lower back pain and lower limb injuryPresented by: Tiziana Resta11:10am-11:15amCellular senescence is similar between regio...
Near-Infrared Spectroscopy (NIRS) and diffuse correlation spectroscopy (DCS) are two established techniques which allow monitoring brain health non-invasively. With the foundation of our seminal NIRS-DCS work on neonates, we are developing novel devices and approaches to better quantify cerebral blood oxygenation, cerebral blood flow and oxygen metabolism in the clinical setting both in children and adults. In particular, in the last few years we have made substantial progress on D...
The following posters will be presented:2:45pm-2:50pmThe Child Focused Injury Risk Screening Tool (ChildFIRST) - Normative Values, Correlations, and Sex Differences for a group of Children aged 8-12Presented by: Matthew B. Miller2:50pm-2:55pmArt-based Rehabilitation Therapy (ART) for Sensorimotor Recovery Post-stroke: A Pilot StudyPresented by: April Christiansen2:55pm-3:00pmWhite matter micros...
Tuesday 11 May, 2021
Sleep is important for memory consolidation and cognitives performances during the day. There is increasing evidence that brain oscillations during sleep play a central role in such processes. This presentation will review recent work from our lab on the interplay between brain rhythms during sleep, memory consolidation and age-related cognitive decline. We will also discuss recent data showing the impact of sleep disturbances on cognitive functions, as well as the effects o...
This talk will discuss sleep of children as they transition to teens in the context of research that examines associations between brain systems that regulate sleep/wake behavior—the circadian timing system and the sleep homeostatic system. For example, adolescents’ circadian timing becomes later; their sleep “need” does not diminish; their sleep homeostatic system is also modified in a way that can modify sleep timing. A major implication of this work has been in the area of education, sp...
The following posters will be presented:10:45am-10:50amThe Belief in Health Benefits of Digital Play Modulates Physiological Responses to Games Played for Cognitive BenefitsPresented by: Sasha Elbaz10:50am-10:55amEffects of Injury Prevention Strategies on the Biomechanics and Neuromuscular Performance of Fundamental Movement Skills in Children and Adolescents.Presented by: John A. Jimenez-Garcia10:55am-11:00am
Circadian clock genes are widely expressed in mammalian brain. Despite considerable knowledge about the role of these genes in the generation of circadian rhythms in the suprachiasmatic nucleus, the master circadian clock, insight into brain-region specific function of these genes limited. Studies in our laboratory investigate the role of core clock gene, Bmal1 and Per2 in the control of behaviors governed by the striatum, a forebrain structure critical in in motor control, reward processi...
Wednesday 12 May, 2021
Regional brain function is determined by its local structure and connectivity. I will present work from our lab that strives to quantify connectivity for applications in healthy development and understanding the impact of disease - focusing on understanding normative cerebellar connectivity and quantifying the impact of stroke. I will also touch on some recent work linking interhemispheric functional connectivity to bimanual motor control in older adults.
The following posters will be presented:10:45am-10:50amMeasurement of Centre of Pressure using the Wii Balance Board in Older Adults with Simulated Visual ImpairmentPresented by: Berkley Peterson10:50am-10:55amDifference in symptom burden and distress among cancer patients undergoing antineoplastic treatmentPresented by: Elizabeth Smyth10:55am-11:00amInfluence of Auditory Load and Beat Perception in Rhythmic A...
Safe mobility is vital to the functional independence of older adults. Executive functions such as working memory updating and dividing attention play an increasingly important role in supporting mobility in old age. This talk describes recent studies that examine the influence of cognitive and sensory challenges to complex motor performance. Featured are recent cognitive training and exercise intervention studies designed to target executive functions to improve mobility and cognition in old...
Thursday 13 May, 2021
An innovative workshop aimed to help attendees develop effective presentation skills. Colleen brings a unique actor’s perspective to communicating with an audience. Effective communication starts with self-awareness, authenticity and passion for the message. The key is learning how to convey these elements in a manner that connects and resonates with the audience. This workshop is highly interactive and includes movement, visualization, warm-up exercises, practice presentations and...
Join us to learn about the multidisciplinary research taking place at the PERFORM Centre from Concordia’s top scientists. The student scientific event subcommittee conducted individual interviews with several PERFORM researchers to learn about their research and academic journey. The interviews will be streamed during the event and will be followed by Q&A session with the researchers to answer any question you may have. We are looking forward to having you!