Skip to main page content

Sexual dimorphism in clock gene function in the striatum

Theme:
Speaker
When:
1:00 PM, Tuesday 11 May 2021 (15 minutes)
Where:
  Virtual session
This session is in the past.
The virtual space is closed.
How:

Circadian clock genes are widely expressed in mammalian brain. Despite considerable knowledge about the role of these genes in the generation of circadian rhythms in the suprachiasmatic nucleus, the master circadian clock, insight into brain-region specific function of these genes limited. Studies in our laboratory investigate the role of core clock gene, Bmal1 and Per2 in the control of behaviors governed by the striatum, a forebrain structure critical in in motor control, reward processing, decision, motivation, and addiction. I will present new data from studies in genetically modified mice demonstrating that Bmal1 and Per2 in the striatum play a sexually dimorphic causal role in the control of alcohol consumption – suppressing intake in males and promoting high intake in females – which may contribute to the known sex differences in alcohol drinking behavior in mice.

Speaker
Concordia University
Professor, Department of Psychology, Affiliate Professor, Department of Biology, Affiliate Professor, Department of Chemistry and Biochemistry
Session detail
Allows attendees to send short textual feedback to the organizer for a session. This is only sent to the organizer and not the speakers.
To respect data privacy rules, this option only displays profiles of attendees who have chosen to share their profile information publicly.

Changes here will affect all session detail pages